Part 45 Article: Biotechnology My Blog Title: The world, from the past to the present, retold from the timelines. Click on PDF to download from Part 3 2023: [8.29] Notable innovations: CRISPR-freebase editing system without guide RNA that enabled also editing chloroplast and mitochondrial genomes with precision (CyDENT). Sourced from [twinkl.com] titled “What is a Chloroplast?” Chloroplasts are mostly oval-shaped blobs, but they can come in shapes like stars and ribbons too. A chloroplast is protected by a smooth outer membrane which holds all of its material. They contain chlorophyll, which is the pigment that gives plants their green colour. Chloroplasts are important to the growth of the plant because they turn sunlight into energy for the plant to use. This is a process called photosynthesis. Chloroplasts are multi-talented. They also store energy for the plant cell and fight off diseases. They are an important part of the cell’s immune system which helps it to stay healthy. Just l...
Part 43 Article: Biotechnology My Blog Title: The world, from the past to the present, retold from the timelines. Click on PDF to download from Part 3 2023: AI in drug development successes: The world's first COVID-19 drug designed by generative AI was approved for human use, with clinical trials expected to begin in China. The new drug, ISM3312, was developed by Insilico Medicine. Understanding the detailed catalytic mechanism of 3CLpro is essential for designing effective inhibitors of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The beauty of generative AI (in drug discovery) was that instead of searching for a needle in a haystack, it generated a bunch of perfect needles for you, Zhavoronkov, InSilico Medicine CEO, said. Then you just had to choose from those perfect needles if you wanted the longer one or the one that was more stable. What made ISM3312 so groundbreaking? It was the world’s first COVID-19 therapeutic created by generative AI. In pr...