Part 25 Article: Biotechnology My Blog Title: The world, from the past to the present, retold from the timelines. Click on PDF to download from Part 3 2023: [10.23] The first successful transplant of a functional cryopreserved mammalian kidney was reported. The study demonstrated a "nano-warming" technique for vitrification for up-to-100 days preservation of transplant organs. Sourced from [frontiersin.org] titled: “Supercooling: a promising technique for prolonged preservation in solid organ transplantation, and early perspectives in vascularized composite allografts.” From the perspective of temperature, machine perfusion can be classified into four categories: HMP “hypothermic machine perfusion” (0°C to 12°C), MMP “mid-thermic machine perfusion” (13°C to 24°C), SNMP “subnormothermic machine perfusion” (25°C to 34°C), and NMP “normothermic machine perfusion” (35°C to 38°C). As metabolic activity increases exponentially with increasing temperature, the required amount of oxy...
Part 22 Article: Biotechnology My Blog Title: The world, from the past to the present, retold from the timelines. Click on PDF to download from Part 3 2023: [10.23] The first successful transplant of a functional cryopreserved mammalian kidney was reported. The study demonstrated a "nano-warming" technique for vitrification for up-to-100 days preservation of transplant organs. Sourced from [https://twin-cities.umn.edu] titled: “Researchers perform first successful transplant of functional cryopreserved rat kidney” Long-term organ banking could increase donor organ utilization, improve donor/recipient matching, enable immune tolerance protocols (reducing the need for immunosuppression drugs), and improve procedure preparation and scheduling. Immunosuppressants are drugs that prevent your immune system from attacking healthy cells and tissues by mistake. Immunosuppressant drugs suppress or reduce the strength of the immune system. Healthcare providers prescribe immunosuppressan...