Part 25 Article: Timeline My Blog Title: The untold the retold Click on PDF to download from Part 1 COLUMN G (476 - 221 BC) Zhou dynasty China Warring States period Duration: 255 years [Total approximate death toll is 2,351,772 for this period based on the mechanisms specified in part 1 and 2 of the timelines] • Carthaginian empire North Africa (650 - 146 BC) • Achaemenid Persia empire or dynasty: Current location Egypt, Balkans and Central Asia (550 - 330 BC) • Roman Republic Italy Rome (509 - 27 BC) • Pandyan dynasty India (500 BC) - 1350 CE • Greco–Persian Wars Greece [death toll 73,800÷2] (499 - 449 BC) • Warring States (China) [death toll 1,341,642÷2] (475 - 221 BC) • Athenian empire Gre...
Part 47 Article: Biotechnology My Blog Title: The world, from the past to the present, retold from the timelines. Click on PDF to download from Part 3 2023: [8.29] Notable innovations: CRISPR-freebase editing system without guide RNA that enabled also editing chloroplast and mitochondrial genomes with precision (CyDENT). In a study published in Nature Biotechnology on Aug. 28, GAO Caixia’s group at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences and her collaborators at Qi Biodesign had reported a modular, CRISPR-free base editing system, which they called CyDENT, to achieve effective base editing in the nucleus, mitochondria and chloroplast genomes of plant and human cells. Genome editing enabled the efficient and precise modification of genetic information in living organisms, revolutionizing life science research as a whole. In recent years, the advent of base editing technology had made genome editing even more precise and predictable. David L...